USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: O00194 USC-OGP 2-DE database:  O00194 O00194 General information about the entry View entry in simple text format Entry name RB27B_HUMAN Primary accession number O00194 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Ras-related protein Rab-27B; AltName: Full=C25KG;. Gene name Name=RAB27B Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0197: pI=4.86; Mw=24929 SPOT OGP-0200: pI=4.84; Mw=24865 SPOT OGP-0201: pI=4.73; Mw=24674 SPOT OGP-0204: pI=4.94; Mw=23927 SPOT OGP-0208: pI=4.93; Mw=23322 Cross-references UniProtKB/Swiss-Prot O00194; RB27B_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name RB27B_HUMAN Primary accession number O00194 Secondary accession number(s) B2RAB0 Q9BZB6 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  March 15, 2017 (version 163) Name and origin of the protein Description RecName: Full=Ras-related protein Rab-27B; AltName: Full=C25KG; Gene name Name=RAB27B Encoded on Name=RAB27B Keywords 3D-structure; Acetylation; Complete proteome; Direct protein sequencing; Disulfide bond; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Polymorphism; Prenylation; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U57093; AAC51194.2; -; mRNA EMBL AF329499; AAK11243.1; -; mRNA EMBL AF498954; AAM21102.1; -; mRNA EMBL AK314115; BAG36807.1; -; mRNA EMBL CH471096; EAW63010.1; -; Genomic_DNA EMBL BC027474; AAH27474.1; -; mRNA CCDS CCDS11958.1; -; . RefSeq NP_004154.2; NM_004163.4; . RefSeq XP_005266790.1; XM_005266733.1; . RefSeq XP_016881402.1; XM_017025913.1; . RefSeq XP_016881403.1; XM_017025914.1; . UniGene Hs.25318; -; . PDB 2F7S; X-ray; 2.70 A; A/B=4-201 PDBsum 2F7S; -; . ProteinModelPortal O00194; -; . SMR O00194; -; . BioGrid 111812; 13; . DIP DIP-48948N; -; . IntAct O00194; 3; . STRING 9606.ENSP00000262094; -; . iPTMnet O00194; -; . PhosphoSitePlus O00194; -; . BioMuta RAB27B; -; . OGP O00194; -; . EPD O00194; -; . MaxQB O00194; -; . PaxDb O00194; -; . PeptideAtlas O00194; -; . PRIDE O00194; -; . DNASU 5874; -; . Ensembl ENST00000262094; ENSP00000262094; ENSG00000041353; . GeneID 5874; -; . KEGG hsa:5874; -; . UCSC uc002lfr.4; human; . CTD 5874; -; . DisGeNET 5874; -; . GeneCards RAB27B; -; . HGNC HGNC:9767; RAB27B; . HPA CAB017712; -; . HPA HPA019849; -; . MIM 603869; gene; . neXtProt NX_O00194; -; . OpenTargets ENSG00000041353; -; . PharmGKB PA34118; -; . eggNOG KOG0081; Eukaryota; . eggNOG ENOG410XQ3T; LUCA; . GeneTree ENSGT00870000136416; -; . HOGENOM HOG000233968; -; . HOVERGEN HBG009351; -; . InParanoid O00194; -; . KO K07886; -; . OMA AEKKCGC; -; . OrthoDB EOG091G0I51; -; . PhylomeDB O00194; -; . TreeFam TF312895; -; . Reactome R-HSA-114608; Platelet degranulation; . Reactome R-HSA-8873719; RAB geranylgeranylation; . Reactome R-HSA-8876198; RAB GEFs exchange GTP for GDP on RABs; . EvolutionaryTrace O00194; -; . GenomeRNAi 5874; -; . PRO PR:O00194; -; . Proteomes UP000005640; Chromosome 18; . Bgee ENSG00000041353; -; . CleanEx HS_RAB27B; -; . ExpressionAtlas O00194; baseline and differential; . Genevisible O00194; HS; . GO GO:0016324; C:apical plasma membrane; IEA:Ensembl; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005795; C:Golgi stack; IDA:UniProtKB; . GO GO:0042470; C:melanosome; IDA:UniProtKB; . GO GO:0032585; C:multivesicular body membrane; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; TAS:Reactome; . GO GO:0031088; C:platelet dense granule membrane; TAS:Reactome; . GO GO:0030141; C:secretory granule; IBA:GO_Central; . GO GO:0030140; C:trans-Golgi network transport vesicle; IDA:UniProtKB; . GO GO:0042589; C:zymogen granule membrane; IEA:Ensembl; . GO GO:0019003; F:GDP binding; IDA:UniProtKB; . GO GO:0005525; F:GTP binding; IDA:UniProtKB; . GO GO:0003924; F:GTPase activity; ISS:UniProtKB; . GO GO:0031489; F:myosin V binding; IPI:UniProtKB; . GO GO:0019904; F:protein domain specific binding; IPI:UniProtKB; . GO GO:0032402; P:melanosome transport; IBA:GO_Central; . GO GO:0071985; P:multivesicular body sorting pathway; IMP:UniProtKB; . GO GO:0002576; P:platelet degranulation; TAS:Reactome; . GO GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB; . GO GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro; . Gene3D 3.40.50.300; -; 1; . InterPro IPR027417; P-loop_NTPase; . InterPro IPR005225; Small_GTP-bd_dom; . InterPro IPR001806; Small_GTPase; . Pfam PF00071; Ras; 1; . SUPFAM SSF52540; SSF52540; 1; . TIGRFAMs TIGR00231; small_GTP; 1; . PROSITE PS51419; RAB; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
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